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Patrick A Ott Selected Research

Immune Checkpoint Inhibitors

1/2022Chemotherapy after immune checkpoint inhibitor failure in metastatic melanoma: a retrospective multicentre analysis.
1/2022Multidimensional Molecular Profiling of Metastatic Triple-Negative Breast Cancer and Immune Checkpoint Inhibitor Benefit.
10/2021Long-term Overall Survival and Predictors in Anti-PD-1-naive Melanoma Patients With Brain Metastases Treated With Immune Checkpoint Inhibitors in the Real-world Setting: A Multicohort Study.
8/2021Cytokine changes during immune-related adverse events and corticosteroid treatment in melanoma patients receiving immune checkpoint inhibitors.
5/2021Impact of COVID-19 on Patients with Cancer Receiving Immune Checkpoint Inhibitors.
1/2021Analyses of PD-L1 and Inflammatory Gene Expression Association with Efficacy of Nivolumab ± Ipilimumab in Gastric Cancer/Gastroesophageal Junction Cancer.
1/2021CX-072 (pacmilimab), a Probody PD-L1 inhibitor, in combination with ipilimumab in patients with advanced solid tumors (PROCLAIM-CX-072): a first-in-human, dose-finding study.
1/2021CX-072 (pacmilimab), a Probody ® PD-L1 inhibitor, in advanced or recurrent solid tumors (PROCLAIM-CX-072): an open-label dose-finding and first-in-human study.
1/2021Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma.
1/2021A multi-center study on safety and efficacy of immune checkpoint inhibitors in cancer patients with kidney transplant.
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Patrick A Ott Research Topics

Disease

78Neoplasms (Cancer)
11/2022 - 01/2010
77Melanoma (Melanoma, Malignant)
01/2022 - 01/2009
13Disease Progression
01/2022 - 05/2015
10Neoplasm Metastasis (Metastasis)
10/2021 - 01/2011
8Renal Cell Carcinoma (Grawitz Tumor)
01/2019 - 03/2013
7Brain Neoplasms (Brain Tumor)
10/2021 - 01/2009
7Colitis
01/2021 - 11/2016
5Pneumonia (Pneumonitis)
08/2021 - 07/2016
5Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2020 - 02/2015
4Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2022 - 06/2017
4Stomach Neoplasms (Stomach Cancer)
01/2021 - 01/2020
4Type 1 Diabetes Mellitus (Autoimmune Diabetes)
04/2005 - 09/2002
3Small Cell Lung Carcinoma (Small Cell Lung Cancer)
01/2020 - 07/2016
3Uveal melanoma
12/2018 - 10/2013
3Exanthema (Rash)
01/2017 - 01/2009
3Hematologic Neoplasms (Hematological Malignancy)
01/2017 - 01/2016
2Lung Neoplasms (Lung Cancer)
01/2022 - 12/2016
2COVID-19
01/2022 - 05/2021
2Inflammation (Inflammations)
01/2019 - 03/2013
2Carcinoma (Carcinomatosis)
01/2019 - 11/2016
2Endometrial Neoplasms (Endometrial Cancer)
12/2017 - 08/2017
2Hypothyroidism
12/2017 - 01/2017
2Hypophysitis
11/2016 - 02/2015
2Fatigue
11/2016 - 01/2009
2Renal Insufficiency (Renal Failure)
07/2016 - 01/2013
2Testicular Neoplasms (Testicular Cancer)
03/2015 - 06/2013
2Infections
03/2013 - 02/2004
2Thrombocytopenia (Thrombopenia)
01/2013 - 01/2009
2Neutropenia
01/2013 - 01/2009
2Chronic Disease (Chronic Diseases)
02/2004 - 09/2002
1Triple Negative Breast Neoplasms
01/2022
1Dermatitis
08/2021
1Dyspnea (Shortness of Breath)
01/2021
1Residual Neoplasm
01/2021
1Urinary Bladder Neoplasms (Bladder Cancer)
10/2020
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2020

Drug/Important Bio-Agent (IBA)

49Immune Checkpoint InhibitorsIBA
01/2022 - 06/2013
25IpilimumabIBA
10/2021 - 06/2013
21pembrolizumabIBA
01/2022 - 02/2015
16VaccinesIBA
01/2022 - 06/2014
14Monoclonal AntibodiesIBA
11/2021 - 03/2013
14NivolumabIBA
10/2021 - 02/2015
12Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2019 - 02/2013
9B7-H1 AntigenIBA
11/2022 - 08/2017
9AntigensIBA
01/2022 - 02/2004
8Proteins (Proteins, Gene)FDA Link
11/2021 - 02/2004
8LigandsIBA
01/2020 - 03/2013
7Biomarkers (Surrogate Marker)IBA
01/2022 - 10/2013
7CytokinesIBA
11/2021 - 09/2002
6Adrenal Cortex Hormones (Corticosteroids)IBA
08/2021 - 02/2015
5Peptides (Polypeptides)IBA
01/2021 - 02/2004
5Cancer VaccinesIBA
11/2020 - 01/2018
5AntibodiesIBA
01/2017 - 01/2014
4EpitopesIBA
01/2021 - 07/2004
4CTLA-4 AntigenIBA
01/2021 - 06/2013
4Pharmaceutical PreparationsIBA
01/2016 - 01/2014
3Neoplasm Antigens (Tumor Antigens)IBA
01/2019 - 06/2014
3CreatinineIBA
01/2019 - 01/2013
3trametinibIBA
01/2016 - 02/2013
3EnzymesIBA
01/2015 - 02/2004
3VemurafenibIBA
07/2013 - 04/2013
2HLA Antigens (Human Leukocyte Antigens)IBA
01/2022 - 01/2021
2L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
10/2021 - 01/2011
2Chimeric Antigen ReceptorsIBA
01/2021 - 01/2019
2ProdrugsIBA
01/2021 - 01/2021
2Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2021 - 01/2017
2Programmed Cell Death 1 ReceptorIBA
01/2021 - 03/2013
2Peptide Hydrolases (Proteases)FDA Link
01/2021 - 01/2021
2Monatide (IMS 3015)IBA
01/2020 - 03/2015
2Glycoproteins (Glycoprotein)IBA
01/2019 - 11/2014
2Immunoconjugates (Immunoconjugate)IBA
01/2019 - 11/2014
2glembatumumab vedotinIBA
01/2019 - 11/2014
2Interleukin-10 (Interleukin 10)IBA
11/2018 - 10/2016
2AutoantigensIBA
01/2018 - 07/2004
2Phosphotransferases (Kinase)IBA
01/2017 - 10/2013
2PlatinumIBA
11/2016 - 07/2016
2Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
01/2016 - 09/2015
2dabrafenibIBA
01/2016 - 01/2014
2Cytotoxins (Cytolysins)IBA
11/2014 - 01/2011
2Mitogen-Activated Protein KinasesIBA
01/2014 - 04/2013
2Dacarbazine (DIC)FDA LinkGeneric
01/2013 - 01/2009
1Circulating Tumor DNAIBA
01/2022
1atezolizumabIBA
01/2022
1MEDI3617IBA
11/2021
1Angiopoietin-2IBA
11/2021
1Immunoglobulin G (IgG)IBA
11/2021
1tremelimumabIBA
11/2021
1Interleukin-17 (Interleukin 17)IBA
08/2021
1CD40 Ligand (CD40L)IBA
08/2021
1TroponinIBA
05/2021
1Protein Subunit VaccinesIBA
01/2021
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2020
1poly ICLCIBA
01/2020

Therapy/Procedure

55Therapeutics
01/2022 - 06/2009
28Immunotherapy
01/2022 - 02/2013
13Drug Therapy (Chemotherapy)
01/2022 - 01/2009
8Radiotherapy
01/2021 - 07/2013
3Aftercare (After-Treatment)
01/2021 - 01/2017
1Lymph Node Excision (Lymph Node Dissection)
01/2021
1Transplantation
01/2020